The PRIME Program

UCSF Internal Medicine Residents can select one of three specialized Areas of Distinction during their second and third years. The largest of these is the Clinical Research Track or PRIME Program, (also known as "Program in Residency Investigation Methods and Epidemiology")

This focuses on outpatient clinical training and clinical research skills. PRIME Residents may go into subspecialty or primary care fields. Residents in PRIME complete an Evidence Based Medicine (EBM) and clinical research curriculum that focuses on research methods, epidemiology, clinical reasoning, and career development. Residents also attend dedicated journal clubs and works in progress sessions. To provide hands on research experience, each resident is paired with a mentor and given protected time to complete a clinical research project during residency.

The goal is to give the residents a chance to "try out" a career in clinical outcomes research during residency by completing an academic "PRIME project". These projects range from educational interventions to secondary data analyses in outcomes research to meta-analysis. Residents pursue topics that they feel passionate about and that can be utilized to become experts in their field. Approximately 60% of PRIME projects are accepted for publication. For more information see: